Ageing Amyloidosis Bone architecture Calcimimetics Calcium cardiovascular Chronic kidney disease Fracture Hemodialysis Hyperparathyroidism Hypocalcemia osteoporosis Oxidative stress Phosphorus Vitamin D
August 31, 2021 by admin
With the increase in the number of ageing population, a number of comorbidities have been seen to be on a rise. Increasing prevalence of chronic kidney disease (CKD) with underlying lifestyle related disorders like hypertension and diabetes mellitus has become a major challenge. CKD– mineral bone disorder (MBD) develops in association with secondary hyperparathyroidism due […]
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Anticoagulation Aortic calcification Bone strength Calcium cardiovascular Carotid artery Coagulation Heart Hydroxyapatite Matrix GLA Osteocalcin osteoporosis
July 22, 2021 by admin
Vitamin K is a cofactor for enzyme, γ-glutamylcarboxylase. This γ-carboxylation allows VKD proteins to bind calcium. Vitamin K is required for the activity of coagulation and anticoagulation factors and for the binding of osteocalcin to hydroxyapatite in bone.1Both forms of vitamin K, K1 and K2, are essential in maintaining blood hemostasis and optimal bone and […]
Bone mass Boron Fragility Magnesium Mineralization Osteoblast Osteogenesis osteoporosis postmenopause Testosterone Vitamin D
July 14, 2021 by admin
Osteoporosis is defined as “a systemic skeletal disease characterized by low bone mass and micro-architectural deterioration with consequent increase in bone fragility and susceptibility to fracture.”1 Osteoporosis is not a life-threatening disorder but still affects many people by causing pain, disability, and diminished quality of life.2 Degrees of skeletal response to boron are modified by other nutritional […]
Bone health Bone homeostasis Bone mineral density Bone resorption Bone tissue Calcification Nutrition Osteoid osteoporosis postmenopause Skeleton Zinc
July 12, 2021 by admin
Zinc, a nutritional trace element, is essential for the growth of human and animals.1 Zinc is required for the growth, development, and maintenance of healthy bones. Bone growth retardation is a common finding in various conditions associated with zinc deficiency.2 In Iranian schoolboys at year 1961, zinc supplementation was first found to restore both skeletal growth and […]
Bone formation Bone mass Bone mineral density Chronic renal disease Hydroxyapatite Magnesium Osteoblast Osteoclast osteoporosis
July 7, 2021 by admin
Osteoporosis is a multifactorial disease characterized by loss of bone mass due to a marked bone microarchitecture deterioration.1 Physiologically, bone is constantly remodeled by concerted and coordinated interactions between osteoclasts, the cells primarily involved in bone resorption, and osteoblasts, which ensure bone formation and mineralization. Osteoporosis results from an imbalance between bone deposition and resorption.1 About […]
Biomarker Calcium Covid Hospital Hypocalcemia Organ injury Parathyroid Septic shock Severity Vitamin D
May 24, 2021 by admin
The pathogen has been reported as a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The World Health Organization (WHO) has made the assessment that coronavirus disease 2019 (COVID-19) can be characterized as a pandemic because the disease is still spreading rapidly around the world, especially in the United States, Spain, and Russia.1 The […]
Calcium Covid Hypocalcemia Hypokalemia Inflammation Organ injury Pneumonia Viral infection
May 20, 2021 by admin
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally.1 Confirmed cases and deaths have been reported in more than 200 countries worldwide.2 While 80% of COVID-19 infections have less severe clinical symptoms (low-grade fever, cough, fatigue) with no evidence of pneumonia or even asymptomatic, those mild or moderate […]
American heart association atherosclerosis blood pressure Calcium cardiovascular heartbeat hypertension osteoporosis postmenopause Vitamin D
May 17, 2021 by admin
Osteoporosis and cardiovascular disease (CVD) are age-related diseases. Traditionally, these two conditions were considered unrelated and their coexistence was attributed to independent age-related processes. However, an increasing body of biological and epidemiological evidence has provided support for a link between the two conditions that cannot be explained by age alone. Shared risk factors, such as […]